342 CHAPTER 7 Estimating Parameters and Determining Sample Sizes 10. Atkins Weight Loss Program In a test of weight loss programs, 40 adults used the Atkins weight loss program. After 12 months, their mean weight loss was found to be 2.1 lb, with a standard deviation of 4.8 lb. Construct a 90% confidence interval estimate of the mean weight loss for all such subjects. Does the Atkins program appear to be effective? Does it appear to be practical? 11. Insomnia Treatment A clinical trial was conducted to test the effectiveness of the drug zopiclone for treating insomnia in older subjects. Before treatment with zopiclone, 16 subjects had a mean wake time of 102.8 min. After treatment with zopiclone, the 16 subjects had a mean wake time of 98.9 min and a standard deviation of 42.3 min (based on data from “Cognitive Behavioral Therapy vs Zopiclone for Treatment of Chronic Primary Insomnia in Older Adults,” by Sivertsen et al., Journal of the American Medical Association, Vol. 295, No. 24). Assume that the 16 sample values appear to be from a normally distributed population and construct a 98% confidence interval estimate of the mean wake time for a population with zopiclone treatments. What does the result suggest about the mean wake time of 102.8 min before the treatment? Does zopiclone appear to be effective? 12. Garlic for Reducing Cholesterol In a test of the effectiveness of garlic for lowering cholesterol, 49 subjects were treated with raw garlic. Cholesterol levels were measured before and after the treatment. The changes (before minus after) in their levels of LDL cholesterol (in mg>dL) had a mean of 0.4 and a standard deviation of 21.0 (based on data from “Effect of Raw Garlic vs Commercial Garlic Supplements on Plasma Lipid Concentrations in Adults with Moderate Hypercholesterolemia,” by Gardner et al., Archives of Internal Medicine, Vol. 167). Construct a 98% confidence interval estimate of the mean net change in LDL cholesterol after the garlic treatment. What does the confidence interval suggest about the effectiveness of garlic in reducing LDL cholesterol? 13. Archeology Archeologists have studied sizes of Egyptian skulls in an attempt to determine whether breeding occurred between different cultures. Listed below are the widths (mm) of skulls from 150 A.D. (based on data from Ancient Races of the Thebaid by Thomson and Randall-Maciver). Construct a 99% confidence interval estimate of the mean skull width. 128 138 126 132 143 135 139 129 14. Minting Quarters Listed below are weights (grams) of quarters minted after 1964 (based on Data Set 40 “Coin Weights” in Appendix B). Construct a 95% confidence interval estimate of the mean weight of all quarters minted after 1964. Specifications require that the quarters have a weight of 5.670 g. What does the confidence interval suggest about that specification? 5.7790 5.5928 5.6486 5.6661 5.5491 5.7239 5.5591 5.5864 5.6872 5.6274 15. Los Angeles Commute Time Listed below are 15 Los Angeles commute times (based on a sample from Data Set 31 “Commute Times” in Appendix B). Construct a 99% confidence interval estimate of the population mean. Is the confidence interval a good estimate of the population mean? 525455540258505530152550 16. Los Angeles Commute Time Repeat the preceding exercise using these 32 Los Angeles commute times: 52545 5 54025 850 5 53015255018 254575604025 8501010301525502030 17. Genes Samples of DNA are collected, and the four DNA bases of A, G, C, and T are coded as 1, 2, 3, and 4, respectively. The results are listed below. Construct a 95% confidence interval estimate of the mean. What is the practical use of the confidence interval? 2 2 1 4 3 3 3 3 4 1
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